Scientist - Biologics_PCR
Full Time
Spring House, PA
Frontage Laboratories
Frontage Laboratories is a CRO/Clinical Research Organization providing integrated, science-driven, product development services throughout the drug discovery and development process to enable life science companies to achieve their drug development goals. We have enabled many innovator, generic and consumer health companies of all sizes to file IND, NDA, ANDA, BLA and 505(b)(2) submissions in global markets allowing for successful development of important therapies and products for patients. We are committed to providing rigorous scientific expertise to ensure the highest quality and compliance. We have successfully assisted clients to advance hundreds of molecules through development to commercial launch in global markets. Come and join us to make a world of difference.
Biologics
Frontage's biologics teams have an average of 10-15 years in complex drug development and have worked with large molecule applications throughout its evolution in product development. We can handle projects for a range of large molecule development projects including peptides, proteins, monoclonal antibodies, bispecific antibodies, biosimilars, oligonucleotides, biomarkers, and antibody drug conjugates.
Gain access to comprehensive biologics services in support of advanced development programs with Frontage's bioanalytical laboratory. We have the capabilities to analyze virtually any peptide, protein, or antibody, and have built a reputation for solving technical challenges related to assay development and validation.
CORE RESPONSIBILITIES:
- Development and optimization of qPCR and RT-qPCR assays
- Perform validations for qPCR and RT-qPCR assays in compliance with SOPs, safety procedures, and federal GLP/GCP guidelines
- Processing of samples for DNA/RNA extraction, DNA/RNA quantification.
- Bioanalysis of non-clinical and clinical samples
- Data analysis, Documentation, and reporting - ELNs, LIMS etc.
May perform other duties as assigned.
Experience/Special Skills:
- Experience with PCR/Molecular Biology is required.
- Understanding of GLP regulations related to assay validation and sample analysis is preferred.
- Experience with digital PCR and instrument automation preferred.
- Experience with electronic lab notebooks and reagent management a plus
- Candidates must be highly organized, independent, and very detail oriented.
- Must be able to multitask and manage multiple projects, willing to learn new techniques, have great time management and communication skills.
Significant Safety or Working Considerations:
May work with potentially infectious samples of human and/or animal origin.
May handle hazardous chemicals.
Educational Requirements:
MS 1-2 years of experience or BS with 3-4 years of experience in biochemistry, biophysics, immunology, molecular biology, analytical chemistry, or a related field.
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.